Mesothelioma Cancer Treatment

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This site contains resources and articles for you to use when you are looking for information about mesothelioma cancer treatment. This site has articles, links to mesothelioma cancer treatment, information and news. In the future we will have reviews of products that will help you make your decision easier with mesothelioma cancer treatment, so you can save time


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Featured Mesothelioma Cancer Treatment Article

Mesothelioma Standard Treatment Options II

By: Govt

Standard treatment options:

  1. Symptomatic treatment to include drainage of effusions, chest tube pleurodesis, or thoracoscopic pleurodesis.
  2. Palliative surgical resection in selected patients.
  3. Palliative radiation therapy.
  4. Single-agent chemotherapy. Partial responses have been reported with doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin, and ifosfamide.
  5. Combination chemotherapy (under clinical evaluation). Information about ongoing clinical trials is available from the NCI Cancer.gov Website.
  6. Multimodality clinical trials.
  7. Intracavitary therapy. Intrapleural or intraperitoneal administration of chemotherapeutic agents (e.g., cisplatin, mitomycin, and cytarabine) has been reported to produce transient reduction in the size of tumor masses and temporary control of effusions in small clinical studies. Additional studies are needed to define the role of intra-cavitary therapy.

The safety and efficacy of pemetrexed, an antifolate, and cisplatin in chemotherapy-n aive patients with malignant mesothelioma who were not eligible for curative surgery was demonstrated in a large phase III randomized trial. This trial compared pemetrexed (500 mg/m2) and cisplatin (75 mg/m2 on day 1) with cisplatin alone (75 mg/m2 on day 1 intravenously every 21 days). A total of 456 patients were enrolled: 226 patients received pemetrexed plus cisplatin and 222 patients received cisplatin alone; 8 patients did not receive therapy. After 117 patients had enrolled, folic acid and vitamin B12 were added to reduce toxic effects. Folic acid (350-1,000 µg orally) was given daily, beginning 1 to 3 weeks before the first chemotherapy dose and continuing daily until 1 to 3 weeks after treatment ended. A vi tamin B12 injection (1,000 µg intramuscularly ) was administered 1 to 3 weeks before the first chemotherapy dose and was repeated approximately every 9 weeks until treatment ended. Dexamethasone (4 mg) or an equivalent corticosteroid was administered orally twice daily for skin rash prophylaxis to all patients 1 day before, on the day of, and 1 day after each pemetrexed dose.

In an analysis of all patients who were randomized and treated, the combination of pemetrexed and cisplatin was associated with a statistically significant improvement in survival compared with cisplatin alone; the median survivals were 1 2.1 versus 9.3 months, respectively (P=.020). The hazard ratio for death of patients in the pemetrexed plus cisplatin arm versus those in the control arm was 0.77. Median time to progression was significantly longer in the pemetrexed plus cisplatin arm (5.7 months vs 3.9 months, P=.001). This superiority in the combination arm was also demonstrated in the vitamin supplemented subgroup. The median survivals were 13.3 and 10.0 months in the combination group and cisplatin alone group, respectively (P=.051). The principal adverse effects of the pemetrexed plus cisplatin regimen were myelosuppression, fatigue, nausea, vomiting, and dyspnea. Mo....[MORE]

 

Sponsored Mesothelioma Cancer Treatment Resources

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Mesothelioma Source - Resource for Asbestos Cancer
Mesothelioma Source offers comprehensive information on types, stages and treatment of malignant mesothelioma ... What is mesothelioma? Mesothelioma is a form of cancer affecting the abdominal cavity, chest cavity, and the region ... Stages. Treatment Options. Clinical Trials. Cancer Centers ...
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National Cancer Institute - Malignant Mesothelioma Treatment
Expert-reviewed information summary about the treatment of malignant mesothelioma ... Malignant Mesothelioma (PDQ®): Treatment. Last Modified: 04/07/2005 ... of recovery) and treatment options. Malignant mesothelioma is a disease in which malignant (cancer) cells form in ...
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Mesothelioma & Asbestos Cancer Resource
What is Mesothelioma? Mesothelioma is a rare disease caused as a result of malignant cancerous cells lining the patient's body cavities such as chest, abdominal region or the area surrounding the heart.
[see more on Mesothelioma & Asbestos Cancer Resource]

Mesothelioma Alternative Cancer Treatment
... Mesothelioma Alternative Cancer Treatment. "My last 3 annual CT scans showed no growth of the cancer ... News. Books. Mesothelioma Alternative Cancer Treatment. The clinic has treated many ...
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Mesothelioma Treatment and Legal Options - Early, Ludwick, Sweeney & Strauss
Early, Ludwick, Sweeney & Strauss offers legal advice and treatment information for people diagnosed with mesothelioma and other asbestos related diseases. ... Effects For Mesothelioma Victims. FDA approves Alimta-Cisplatin Combination for treatment of Asbestos-Related Cancer ... be at risk to develop malignant mesothelioma. Learn More ...
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MesoLink.org -- Your Link To Mesothelioma Information
... can provide important and in-depth Mesothelioma and cancer related information, and a legal guide to ... drug for the treatment of malignant pleural mesothelioma ( Altima ), which is a ...
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Mesothelioma Cancer Treatment
... Mesothelioma. Malignant mesothelioma is a rare cancer that affects the cells lining various organs ... Because of the aggressive nature of malignant mesothelioma, treatment is difficult ...
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Mesothelioma - Wikipedia, the free encyclopedia
... Mesothelioma is an uncommon form of cancer, usually associated with previous exposure to ... to help plan treatment. Mesothelioma is described as localized if the cancer is found only ...
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Mesothelioma Cancer Treatment News

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Mesothelioma Treatment | Doctors, Cancer Centers & Clinical Trials
Find new mesothelioma treatment options including Alimta® here. Also review clinical
trials.
http://www.mesothelioma.com/treatment/
 
Mesothelioma Treatment Center: Latest Treatment News and Information
Mesothelioma Treatment Center. Information about Mesothelioma cancer treatments: drugs,
chemotherapy, radiation and surgery treatments.
http://www.mesothelioma-cancer-treatment.com/
 
Alternative Treatments | Options for Mesothelioma Patients
Alternative Mesothelioma Treatment Options can be very beneficial for those suffering from
mesothelioma cancer and include TENS Therapy, Massage, Meditation, Yoga ...
http://www.mesothelioma.com/treatment/alternative/
 
Mesothelioma Survival Rate: Ways to Extend Your Life Expectancy
Assistance with Doctor & Cancer Centers: Many times it can be difficult to find top
doctors and cancer centers that specialize in the treatment of mesothelioma.
http://www.mesotheliomasurvivalrate.net/
 

 

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