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Featured Mesothelioma Definition Article

Stage 1 Mesothelioma

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1. Stage Information

Patients with stage I disease have a significantly better prognosis than those
with more advanced stages. However, because of the relative rarity of this
disease, exact survival information based upon stage is limited. A proposed
staging system based upon thoracic surgery principles and clinical data is
shown below. It is a modif ication of the older system proposed by Butchart
et al. Other staging systems that have been employed, including a proposed
new international TNM staging system, are summarized by the International
Mesothelioma Interest Group.

• Stage I: Disease confined within the capsule of the parietal pleura:
  ipsilateral pleura, lung, pericardium, and diaphragm.
• Stage II: All of stage I with positive intrathoracic (N1 or N2) lymph nodes.
• Stage III: Local extension of disease into the following: chest wall or
  mediastinum; heart or through the diaphragm, peritoneum; with or without
  extrathoracic or contralateral (N3) lymph node involvement.
• Stage IV: Distant metastatic disease.

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