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Mesothelioma Standard Treatment Options II
By: Govt
Standard treatment
options:
- Symptomatic treatment to include drainage of effusions,
chest tube
pleurodesis, or thoracoscopic pleurodesis.
- Palliative surgical resection
in selected patients.
- Palliative radiation therapy.
- Single-agent chemotherapy. Partial responses have been reported with
doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin,
and ifosfamide.
- Combination chemotherapy (under clinical evaluation). Information
about ongoing clinical trials is available from the NCI
Cancer.gov Website.
- Multimodality clinical trials.
- Intracavitary
therapy. Intrapleural or intraperitoneal administration
of
chemotherapeutic agents (e.g., cisplatin, mitomycin,
and cytarabine) has been
reported to produce transient
reduction in the size of tumor masses and
temporary control of effusions in small clinical studies. Additional
studies are needed to define the role of intra-cavitary therapy.
The safety and efficacy of pemetrexed, an antifolate, and
cisplatin in chemotherapy-n aive patients with malignant mesothelioma
who were not eligible for curative
surgery was demonstrated in a large phase III randomized trial. This
trial compared pemetrexed (500 mg/m2) and cisplatin (75
mg/m2 on day 1) with cisplatin alone (75 mg/m2 on day 1 intravenously every 21 days). A total of 456 patients
were enrolled: 226 patients received pemetrexed plus cisplatin and 222 patients
received cisplatin alone; 8 patients did not receive therapy.
After 117 patients had enrolled, folic acid and vitamin B12 were added to reduce toxic effects. Folic acid (350-1,000 µg orally)
was given daily, beginning 1 to 3 weeks before the first chemotherapy dose and
continuing daily until 1 to 3 weeks after treatment ended. A vi
tamin B12 injection (1,000 µg intramuscularly
) was administered 1 to 3 weeks before the first chemotherapy dose and was repeated
a....[MORE]
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| ACS :: Mesothelioma Drug Approved The US Food and Drug Administration has approved the drug Alimta for treatment of malignant mesothelioma, a cancer of the lining of the chest and abdomen.
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| New Drug for Mesothelioma ... New Drug for Mesothelioma. Category: News ... The FDA recently approved a new drug used to treat malignant pleural mesothelioma, a rare cancer usually associated with ...
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| Mesothelioma Reporter: New Mesothelioma Drug SBP002 Mesothelioma Reporter provides balanced reporting on mesothelioma news and information. New Mesothelioma Drug SBP002 ... September 16, 2004. New Mesothelioma Drug SBP002 ... The SBP002 mesothelioma treatment drug is derived from the noxious weed Devil's Apple. ...
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| MesoLink.org -- Your Link To Mesothelioma Information ... Mesothelioma is one of the deadliest diseases known to man; the average life span of an ... FEATURED NEWS: New Mesothelioma Drug Approval ...the FDA (Food and Drug Administration) in ...
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| Mesothelioma Treatment - Alimta (pemetrexed) Drug Therapy Mesothelioma treatment options using drugs and chemotherapy involving Alimta alone and in combination with other cancer fighting drugs. ... Mesothelioma Treatments - Asbestos Attorney | Monday, November 07, 2005 ... Specific Mesothelioma Drug / Chemotherapy Treatments ...
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| First U.S. mesothelioma drug approved The U.S. Food and Drug Administration (FDA) on February 4, 2004, approved Alimta (pemetrexed disodium) for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma, a rare type of cancer. It is the first... First U.S. mesothelioma drug approved. Rare/Orphan Diseases Blog ...
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| Rare/Orphan Diseases A comprehensive site providing information and links for rare and orphan diseases. ... The U.S. Food and Drug Administration (FDA) on October 31, 2005, approved orphan drug designation for ZED6474 (Zactima ... Medicines Evaluation Agency for orphan drug status in Europe ...
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| Mesothelioma Treatment Options - Drug Therapy Mesothelioma chemotherapy treatments with onconase, lovastatin, megace, pemetrexed and cisplatin. ... Specific Mesothelioma Drug / Chemotherapy Treatments: ...
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| Mesothelioma drug, Alimta, may help patients Mesothelioma Drug Alimta - Personal Injury law firm representing injured people in Pittsburgh, Pennsylvania, Ohio, Maryland and West Virginia for over 35 years. ... Mesothelioma Drug Alimta. A clinical study has shown positive results when the new mesothelioma drug Alimta was used with traditional ...
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| Mesothelioma Cancer Drugs | Mesothelioma cancer drugs are used for chemotherapy. Some victims of mesothelioma (asbestos cancer) are too far advanced or too weak to be treated with surgery or radiotherapy ... | | http://mesotheliomacancerdrugs.org/ | | | | Mesothelioma Information from Drugs.com | Mesothelioma information from Drugs.com, including Mesothelioma treatment options and diagnosis. | | http://www.drugs.com/mesothelioma.html | | | | Mesothelioma Drugs | Mesothelioma drugs are used for chemotherapy. Some victims of asbestos cancer (mesothelioma) are too far advanced or too weak to be treated with surgery or radiotherapy ... | | http://mesotheliomadrugs.org/ | | | | Mesothelioma Drugs - Chemotherapy Medications ... | Medications are commonly used by mesothelioma patients. The use of chemotherapy drugs and pain medications are often recommended by doctors. | | http://www.asbestos.com/treatment/drugs.php | | |
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