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Mesothelioma Treatment Overview
By:
Treatment Option Overview
Standard treatment for all but localized mesothelio
ma is generally not
curative. Although some patients will experience long-term survival with
aggressive treatme
nt approaches, it remains unclear if overall survival has
been significantly altered by the different treatment
modalities or by
combinations of modalities. Extrapleur
al pneumonectomy in selected patients
with early stage disease may improve recurrence-free survival, but its impact
on overall survival is unknown. Pleurectomy and
decortication can provide
palliative relief from symptomatic effusions, discomfort caused by tumor
burden, and
pain caused by invasive tumor. Operative mortality from
pleurectomy/decortication is less than 2%, while mortality from extrapleural
pneumonectomy has ranged from
6% to 30%. The addition of radiation
therapy and/or chemotherapy following surgical intervention has not
demonstrated improved survival. The use of radiatio
n therapy in pleural
mesothelioma has been shown to alle
viate pain in the majority of patients
treated. However, the duration of symptom control is short-lived.
Single
agent and combination chemotherapy have been evaluated in single and combined
modality studies. The most studied agent is doxorubicin, which has produced
partial responses in approximately 15% to 20% of patients studied. Some
combination chemotherapy regimens have been reported to have higher response
rates in small phase II trials. However the toxicity reported is also higher
and there is no evidence that combination regimens result in longer survival
or
longer control of symptoms. Recurrent pleural effusions may be treated
with pleural sclerosing procedures; however, failure rates are
usually
secondary to the bulk of the tumor, which precludes pleural adhesion due to the
inability of the lung to fully expand.
The designations in PDQ that treatments are ìstandardî or ìunder clinical
evaluationî are not to be used as
a basis for reimbursement determinations.
....[MORE]
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| Mesothelioma Mesothelioma ... Diagnosis Death Clinic Claim Chemotherapy Cause Case Attorney Asbestos Abdominal Verdicts. Mesothelioma wie wenn ... erzählen trials falls erwarten (research indem fehlen studies je ...
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| Treatment of Mesothelioma at Mayo Clinic Mesothelioma. Research. Treatment of Mesothelioma. at Mayo Clinic. (Synonyms: Asbestos-related cancer, pleural cancer, pleural malignant mesothelioma, sarcomatous mesothelioma, epithelial mesothelioma, mixed mesothelioma) ... over the world refer patients with mesothelioma to Mayo Clinic. Mayo's strength lies in the ability ... Mayo Clinic physicians are actively engaged in research related to mesothelioma. ...
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| Mesothelioma Research - Mayo Clinic | Link to this article. To link to this article, paste this block of HTML code onto your webpage. Guidelines for sites linking to mayoclinic.org | | http://www.mayoclinic.org/mesothelioma/research.html | | | | Mesothelioma research clinic | Please check with a mesothelioma research clinic or a mesothelioma specializing doctor if you think that you have mesothelioma. | | http://www.mesotheliomaresearch.ca/ | | | | Mesothelioma - MayoClinic.com | Mesothelioma ? Comprehensive overview covers malignant ... 2010 Mayo Foundation for Medical Education and Research ... Enhance your life," and the triple-shield Mayo Clinic ... | | http://www.mayoclinic.com/health/mesothelioma/DS00779 | | | | Mesothelioma Clinics | Mesothelioma and Asbestos Cancer Resources | Mesothelioma & Pets; Mesothelioma Research; Mesothelioma Statistics ... Like most illness research and medical centers, Mayo Clinic pioneers itself as one of the most ... | | http://www.maacenter.org/mesothelioma/clinics/ | | | | Mesothelioma Clinics - Find a Cancer Center Near You | Mesothelioma Clinics information resource and guide for our nations top cancer centers. ... the U.S., including 58 that offer patient care and seven that conduct research only. | | http://www.mesothelioma.com/cancer_centers.htm | | | | Mesothelioma Research | Mesothelioma Research Clinics. Since the late 1970s, the number of research clinics specializing in mesothelioma cancer has increased significantly. | | http://www.mesothelioma-information-and-hope.com/Mesothelioma-Research.html | | |
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