Mesothelioma Information Directory

Author: U. S. Govt

Employers are required to follow regulations dealing with asbestos exposure

on the job that have been issued by the Occupational Safety and Health Administration

(OSHA), the Federal agency respon sible for health and safety regulations

in maritime, construction, manufacturing, and service workplaces. The Mine

Safety and Health Administration (MSHA) enforces regulations related to

mine safety. Workers should use all protective equipment provided by

their employers and foll ow recommended work practices and safety procedures.

For example, National Institute of Occupational Safety and Health (NIOSH)-approved

respirators that fit properly should be worn by workers when required.

Workers who are concerned about asbestos exposure in the workplace should

discuss the situation with other employees, their employee health and safety

representative, and their employers. If n....[MORE]

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Asbestos kills navy vet
The grieving relatives of a Portishead veteran are hoping that an inquest into his death will save lives by raising the profile of a ‘devastating’ disease.

Ken Batty, of Manor Close, served his country in the Royal Navy for 14 years after joining as an apprentice in 1951. By the time he left [...]

As he sits at his kitchen table with his tray full of medicine that he must take to keep breathing, Rochester Steverson, of Pittsburgh's Windgap neighborhood, is hoping he does not become the kind of statistic kept by the federal government.

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Get current information on mesothelioma including treatment options and legal options. Includes free links to helpful websites.
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WASHINGTON -- A congressional effort to cope with the burgeoning number of asbestos lawsuits would end a program in Maryland that has been hailed as a model for streamlining the legal process for victims of asbestos-related diseases.

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Author: U.S. Govt.

1. What is asbestos?

?Asbestos? is the name given to a group of minerals that occurnaturally

as bundles of fibers which can be separated into thinthreads. These fibers

are not affected by heat or chemicals and do not conduct electricity. For

these reasons, asbestos has been widely used in many industries. Four types

of asbestos have been used commercially:





• Chrysotile, or white asbestos;
  

  
  

• Crocidolite, or blue asbestos;
  

  
  

• Amosite, which usually has brown fibers; and
  

  
  

• Anthophyllite, which usually has gray fibers.

Chrysotile asbestos, with its curly fibers, is in the serpentinefamily of

minerals. The other types of asbestos, which all have rod-like fibers, are

known as amphiboles.

Asbestos fiber masses tend to break easily into a dust composed of tiny

particles that can float in the air and stick toclothes. The f ibers may

be easily inhaled or swallowed and can causes erious health problems.

2. How is asbestos used?
3. What are the health hazards of exposure to asbestos?

Exposure to asbestos may increase the risk of several serious diseases:





• Asbestosis? a chronic

  lung ailment that can produce shortness of b....[MORE]

Author: Govt

Researchers with the largest phase III trial

to date for mesothelioma, an aggressive cancer affecting the lining of

the lung, reported results showing that patients on a new chemotherapy

drug regimen

live longer and have less pain than those on an older drug. The

findings were announced at the annual meeting of the American Society

of Clinical Oncology meeting in Orlando, Fla., on May 20, 2002.

Pemetrexed

(brand name AlimtaŸ) is a novel antifolate, a class of drugs that

targets the folic acid metabolic pathway, which effects availability of

certain B complex vitamins. The results of the trial show that tumors

shrank in 41 percent of patients on pemetrexed in combination with a

more commonly used chemotherapy agent called cisplatin.

Only 17 percent of patients receiving cisplatin alone experienced tumor

shrinkage. Additionally, those on the pemetrexed combination lived

nearly three months longer than those on cisplatin alone.

According

to lead author, Nicholas J. Vogelzang, M.D., University of Chicago

Cancer Research Center, "This is the largest clinical trial ever

conducted in this disease and the 25 to 30 percent improvement in

survival for patients on the combination therapy is the first time

anyone has documented a significant improvement in patients treated for

mesothelioma."

Malignant pleural mesothelioma is associated with a history of asbestos

exposure in about 70 to 80 percent of all cases and there is no

approved or very effective chemotherapy for the disease. Researchers

hypothesized that pemetrexed....[MORE]

Sometimes the ironic timing of events in our public life is so striking as to cause one to wonder whether the Great Scriptwriter in the Sky is trying to make a point. Thus, the word that the Senate voted for tort deform last week came just a few days after ...

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The Senate Judiciary Committee today approved S.852, the Fairness in Asbestos Injury Resolution Act (FAIR Act), a bill that will establish a trust fund for victims with asbestos-related diseases like asbestosis and mesothelioma. Charles G. Hardin, president of RetireSafe, issued the following statement in response to today's Judiciary Committee action

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Author: Govt.

Mesothelioma is a rare form of cancer in which malignant (cancerous) cells are found in the

mesothelium, a protective sac that covers most of the body's internal organs. Most people who develop

mesothelioma have worked on jobs where they inhaled asbestos particles.

1. What is the mesothelium?

The mesothelium is a membrane that covers and protects most of the internal organs of the body. It

is composed of two layers of cells: One layer immediately surrounds the organ; the other forms a sac

around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing

moving organs (such as the beating heart and the expan....[MORE]

Alfacell Corporation , a biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics for cancer and other life-threatening diseases, today announced that Kuslima Shogen, Chairman and Chief Executive Officer, addressed the closing session of the 7th International Meeting on Ribonucleases in Stara Lesna, Slovak Republic yesterday evening.

The family of the late paleontologist and evolutionary scientist Stephen Jay Gould sued two Boston hospitals and three doctors, alleging the famed author would still be alive if they had properly diagnosed his cancer.

Author: U.S. Govt.

Asbestos was mined and used commercially in North America beginning in the

late 1800s. Its use increased greatly during World WarII. Since then, it

has been used in many industries. For example, thebui lding and construction

industry has used it for strengthening cementand plastics as well as for

insulation, fireproofing, and sound absorption. The shipbuilding industry

has used asbestos to insulate boilers, steampipes, and hot water pipes. The

automotive industry uses asbestos in vehicle brakeshoes and clutch pads.

More

than 5,000 products contain or have contained asbestos. Some of them are

listed below:

• Asbestos cement sheet and pipe products used for water supply and sewage

  piping, roofing and siding, casings for electrical wires, fire protection

  material, electrical switchboards and components, and residential and industrial

  building materials;

• Friction products, such as clutch facings, brake linings for automobiles,

  gaskets, and industrial friction materials;

• Products containing asbestos paper, such as table pads and heat-protective

  mats, heat and electrical wire insulation, industrial filters for beverages,

  and under lying material for sheet flooring;

• Asbestos textile products, such as packing components, roofing materials,

  and heat- and fire-resistant fabrics(including blankets and curtains);

  and

• Other products, including ceiling and floor ....[MORE]

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Proponents of a bill to rein in asbestos lawsuits say this could be the year legislation is finally approved on Capitol Hill. Court cases have cost companies billions of dollars, while also helping to push dozens of firms into bankruptcy. But given the mounting debate over the proposed legislation, ...

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(OPENPRESS) May 12, 2005 — “Our site is designed specifically with our customers in mind, the people and their loved ones who suffer from Mesothelioma, and to provide them with information on symptoms and diagnosis of malignant mesothelioma treatments and suggests the best options for making their legal claim” says David Reed of Mesthelioma-information (http://mesothelioma-information.atspace.com)
Mesothelioma [...]

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Author:

Standard treatment

options:

1. Symptomatic treatment to include drainage of effusions,

   chest tube

   pleurodesis, or thoracoscopic pleurodesis.

2. Palliative surgical resection

   in selected patients.

3. Palliative radiation therapy.
4. Single-agent chemotherapy. Partial responses have been reported with

   doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin,

   and ifosfamide.

5. Combination chemotherapy (under clinical evaluation). Information

   about ongoing clinical trials is available from the NCI

   Cancer.gov Website.

6. Multimodality clinical trials.
7. Intracavitary

   therapy. Intrapleural or intraperitoneal administration

   of

   chemotherapeutic agents (e.g., cisplatin, mitomycin,

   and cytarabine) has been

   reported to produce transient

   reduction in the size of tumor masses and

   temporary control of effusions in small clinical studies. Additional

   studies are needed to define the role of intra-cavitary therapy.

The safety and efficacy of pemetrexed, an antifolate, and

cisplatin in chemotherapy-n aive patients with malignant mesothelioma

who were not eligible for curative

surgery....[MORE]

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Author: U.S. Govt.

?Asbestos? is the name given to a group of minerals that occur naturally

as bundles of fibers which can be separated into thinthreads. These fibers

are not affected by heat or chemicals and do not conduct electricity. For

these reasons, asbestos has been widely used in many industries. Four types

of asbestos have been used commercially:

• Chryso tile, or white asbestos;
  

  
  

• Crocidolite, or blue asbestos;
  

  
  

• Amosite, which usually has brown fibers; and
  

  
  

• Anthophyllite, which usually has gray fibers.

Chrysotile asbestos, with its curly fibers, is in the serpentine family of

minerals. The other types of asbestos, which all have rod-like fibers, are

known as amphiboles.

Asbestos fiber masses tend to break easily into a dust composed of tiny

particles that can float in the air and stick toclothes. The fibers may

be easily inhaled or swallowed and can cause serious health problems.

....[MORE]

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The Senate Judiciary Committee today approved S.852, the Fairness in Asbestos Injury Resolution Act (FAIR Act), a bill that will establish a trust fund for victims with asbestos-related diseases like asbestosis and mesothelioma. Charles G. Hardin, president of RetireSafe, issued the following statement in response to today's Judiciary Committee action

Mesothelioma resources, help and information. We have researched all the web sites related to mesothelioma and brought them together in one place for easy access.
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Author: Govt

Standard treatment

options:

1. Symptomatic treatment to include drainage of effusions,

   chest tube

   pleurodesis, or thoracoscopic pleurodesis.

2. Palliative surgical resection

   in selected patients.

3. Palliative radiation therapy.
4. Single-agent chemotherapy. Partial responses have been reported with

   doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin,

   and ifosfamide.

5. Combination chemotherapy (under clinical evaluation). Information

   about ongoing clinical trials is available from the NCI

   Cancer.gov Website.

6. Multimodality clinical trials.
7. Intracavitary

   therapy. Intrapleural or intraperitoneal administration

   of

   chemotherapeutic agents (e.g., cisplatin, mitomycin,

   and cytarabine) has been

   reported to produce transient

   reduction in the size of tumor masses and

   temporary control of effusions in small clinical studies. Additional

   studies are needed to define the role of intra-cavitary therapy.

The safety and efficacy of pemetrexed, an antifolate, and

cisplatin in chemotherapy-n aive patients with malignant mesothelioma

who were not eligible for curative

surgery was demonstrated in a large phase III randomized trial. This

trial compared pemetrexed (500 mg/m²) and cisplatin (75

mg/m² on day 1) with cisplatin alone (75 mg/m² on day 1 intravenously every 21 days). A total of 456 patients

were enrolled: 226 patients received pemetrexed plus cisplatin and 222 patients

received cisplatin alone; 8 patients did not receive therapy.
.....[MORE]

Author: U.S. National Library of Medicine

Definition

Benign mesothelioma is a noncancerous tumor

of the pleura (lining of the lung and chest cavity).

Causes, incidence, and risk factors

Nonmalignant mesothelioma is usually a localized

tumor that affects men more frequently than women. The tumor may grow to a large

size and compress the lung, causing the symptoms of shortness of breath.

Symptoms

• chronic

  cough

• shortness of breath

• chest pain

Signs and tests

During a physical examination, the health care provider may notice a clubbed appearance of the fingers.

Tests that may show mesothelioma include the following:

• Chest X-ray

• CT scan of the chest

• Open lung biopsy

Treatment

Surgery is usually necessary for a solitary tumor.

[MORE]

The family of the late paleontologist and evolutionary scientist Stephen Jay Gould sued two Boston hospitals and three doctors Friday, alleging the famed author would still be alive if they had properly diagnosed his cancer four years ago.

Given the advancing age of our surviving World War II veterans, time is short for these particular victims of asbestos-related illnesses.

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On the subject of blog business models, Michael Buffington explains how he launched Asbestos News, a niche content blog designed to generate money via Google AdWords based on content supplied by Google Alerts:

The subject matter, while weighty and all that, is of little importance to ...

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Consumer resource provides information and access to legal counsel for those suffering from asbestos exposure.
Seattle, WA (PRWE December 16, 2004 – Mesotheliomasos.com is a recently developed website that provides information and resources for Mesothelioma victims, including the causes, risk factors and warning symptoms associated with the disease. In addition, the site also offers a free [...]

Mesothelioma resources, help and information. We have researched all the web sites related to mesothelioma and brought them together in one place for easy access.
1st-in-mesothelioma.org

Author: U.S. National Library of Medicine
1.

Recruiting

Combination

Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma

Conditions:

localized malignant mesothelioma; advanced malignant mesothelioma;

recurrent malignant mesothelioma; epithelial mesothelioma; ...

2.

Recruiting

Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma

Conditions:

localized malignant mesothelioma; recurrent malignant mesothelioma;

epithelial mesothelioma; sarcomatous mesothelioma

-1">3.[MORE]

Author:
Treatment Option Overview

Standard treatment for all but localized mesothelio

ma is generally not

curative. Although some patients will experience long-term survival with

aggressive treatme

nt approaches, it remains unclear if overall survival has

been significantly altered by the different treatment

modalities or by

combinations of modalities. Extrapleur

al pneumonectomy in selected patients

with early stage disease may improve recurrence-free survival, but its impact

on overall survival is unknown. Pleurectomy and

decortication can provide

palliative relief from symptomatic effusions, discomfort caused by tumor

burden, and

pain caused by invasive tumor. Operative mortality from

pleurectomy/decortication is less than 2%, while mortality from extrapleural

pneumonectomy has ranged from

6% to 30%. The addition of radiation

therapy and/or chemotherapy following surgical intervention has not

....[MORE]

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The Senate Judiciary Committee today approved S.852, the Fairness in Asbestos Injury Resolution Act (FAIR Act), a bill that will establish a trust fund for victims with asbestos-related diseases like asbestosis and mesothelioma. Charles G. Hardin, president of RetireSafe, issued the following statement in response to today's Judiciary Committee action

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Less than two months after a winning a landmark case for asbestos victims, 71-year-old Bill Ewins has died. A memorial service is being held in Adelaide today, following his death on Saturday.

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Author: OEHHA

• Most of the information on health effects comes from studies of workers

  exposed regularly to high levels of asbestos. In occupational settings

  all forms of asbestos

  have been shown to cause asbestosis, lung cancer and mesothelioma. Asbestosis

  is a noncancerous lung disease involving diffuse fibrotic scarring of the

  lungs. Persons with asbestosis can experience progressive shortness of

  breath. Lung

  cancer is associated with asbestos exposures; cigarette smoking and asbestos

  exposure multiply the risk of lung cancer beyond that caused by exposure

  to either of these materials separately. Mesothelioma is an incurable cancer

  of the lining

  of the chest cavity and abdomen.
  

• People have been exposed to asbestos by living with asbestos workers or

  living in the vicinity of asbestos mines and factories. People exposed to

  asbestos in

  such non-occupational settings have also had asbestos-related diseases including

  cancer. While most asbestos-associated cancers are related to the intensity

  and duration of exposure, reports in medical journals have linked some mesotheliomas

  to short exposure periods, on the order of months. Even in these cases, however,

  usually many years (20 years or more) elapse between the time of initial

  exposure

  to asbestos and the development of mesothelioma. In addition, there....[MORE]

Author:

1. Stage Information

Patients with stage I disease have a significantly better prognosis

than those

with more advanced stages. However, because of the relative rarity of this

disease, exact survival information based upon stage is limited. A proposed

staging system based upon thoracic surgery principles and clinical data is

shown below. It is a modif ication of the older

system proposed by Butchart

et al. Other staging systems that have been employed, including a proposed

new international TNM staging system, are summarized by the International

Mesothelioma Interest Group.

• Stage I: Disease confined within the capsule of the

  parietal pleura:
  

  ipsilateral pleura, lung, pericardium, and diaphragm.

• Stage II: All of stage I with positive intrathoracic

  (N1 or N2) lymph nodes.

• Stage III: Local extension of disease into the following:

  chest wall or
  

  mediastinum; heart or through the diaphragm, peritoneum; with or without
  

  extrathoracic or contralateral (N3) lymph node involvement.

• Stage IV: Distant metastatic disease.

....[MORE]

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The law firm of Baron & Budd, P.C. is pleased to announce the launch of Mesotelioma en Espanol , a Spanish-language Web site created to provide medical and legal information for Spanish-speaking victims of mesothelioma and their families.

Deaths from mesothelioma, an asbestos-related lung cancer, will peak within ten years in the UK and then fall to a much lower level, according to new figures published in this week's British Journal of Cancer. Mesothelioma is a type of cancer in the lining of the lungs or the lining ...

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Author: Govt

Researchers with the largest phase III trial

to date for mesothelioma, an aggressive cancer affecting the lining of

the lung, reported results showing that patients on a new chemotherapy

drug regimen

live longer and have less pain than those on an older drug. The

findings were announced at the annual meeting of the American Society

of Clinical Oncology meeting in Orlando, Fla., on May 20, 2002.

Pemetrexed

(brand name AlimtaŸ) is a novel antifolate, a class of drugs that

targets the folic acid metabolic pathway, which effects availability of

certain B complex vitamins. The results of the trial show that tumors

shrank in 41 percent of patients on pemetrexed in combination with a

more commonly used chemotherapy agent called cisplatin.

Only 17 percent of patients receiving cisplatin alone experienced tumor

shrinkage. Additionally, those on the pemetrexed combination lived

nearly three months longer than those on cisplatin alone.

According

to lead author, Nicholas J. Vogelzang, M.D., University of Chicago

Cancer Research Center, "This is the largest clinical trial ever

conducted in this disease and the 25 to 30 percent improvement in

survival for patients on the combination therapy is the first time

anyone has documented a significant improvement in patients treated for

mesothelioma."

Malignant pleural mesothelioma is associated with a history of asbestos

exposure in about 70 to 80 percent of all cases and there is no

approved or very effective chemotherapy for the disease. Researchers

hypothesized that pemetrexed ....[MORE]

Author:

General Information

Prognosis in this disease is

difficult to assess consistently because
there is gre

at variability in the time before diagnosis and the rate

of disease
progression. Various surgical procedures ma

y be possible in selected patients,
providing long-term

survival without cure. In large retrospective series of

pleural mesothelioma patients, important prognostic factors were found to be

stage, age, performance status, and histology.

For patients treated with aggressive

surgi

cal approaches, factors associated with improved long-term

survival include epithelial histology, negative lymph

nodes, and negative

surgical margins. For those patients

treated with aggressive surgical approaches,

nodal stat

us is an important prognostic factor. Median survival for

malignant

local pleural disease has been reported as 16

months

and extensive disease as 5 months. In some inst

ances the tumor grows through the

diaphragm making the s

ite of origin difficult to assess.

Cautious interpretat

ion of treatment results in this disease is imperative because of

the selection differences among series. Effusions, both pleural and

peritoneal, represent major sympt

omatic problems for at least two thirds of the

patients.

A history of asbestos exposure is reported in about 70

% to 80% of

all cases of mesothelioma.

.....[MORE]

The Senate Judiciary Committee today approved S.852, the Fairness in Asbestos Injury Resolution Act (FAIR Act), a bill that will establish a trust fund for victims with asbestos-related diseases like asbestosis and mesothelioma. Charles G. Hardin, president of RetireSafe, issued the following statement in response to today's Judiciary Committee action

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The family of the late paleontologist and evolutionary scientist Stephen Jay Gould sued two Boston hospitals and three doctors Friday, alleging the famed author would still be alive if they had properly diagnosed his cancer four years ago.

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They're getting ready for the Asbestos Health Fair in this old mining town. Posters promise "Door Prizes!!" and "Blood draw to participate in ongoing research!" Companies that sell home oxygen supplies will send reps. Doctors and researchers will be here. There will be consultants to help asbestosis victims apply for ...

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Author: Govt.

Mesothelioma is a rare form of cancer in which malignant (cancerous) cells are found in the

mesothelium, a protective sac that covers most of the body's internal organs. Most people who develop

mesothelioma have worked on jobs where they inhaled asbestos particles.

1. What is the mesothelium?

< ....[MORE]

Author: Rich McIver

Lewis and Sholnick have announced the publication of some simple precautionary steps can be taken to avoid high risk situations in regards to asbestos and mesothelioma.

Mesothelioma is a rare form of cancer caused by exposure to asbestos. It refers specifically to a cancerous tumor which involves the mesothelial cells of an organ, usually the lungs or abdomen. Despite being classified under the rather broad category of cancer, however, Mesothelioma is unique for a number of reasons. First is the immense devastation of the disease, and the inability for modern medical techniques to significantly slow its onset or offer a cure. Approximately 75% of patients die within 18 months of the first signs of the disease. Second, is the long latency period between exposure to the cause of the disease, asbestos, and its onset. Latency runs the gamut from 15 to 50 years, meaning that a person may have been exposed to asbestos more than a half century before the first serious signs of the disease manifest themselves. The avera....[MORE]

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In the 60's workers began to hear about the dangers of working around asbestos and the devastating effects of a cancer called Mesothelioma. Mesothelioma is a cancer of the cells most frequently found along the lining of the lungs is still extremely deadly today.

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Legislation that pleases neither asbestos victims nor the corporations liable for their exposure has easily passed committee, but public health advocates say the measure is geared to relieve guilty companies of responsibility.

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Author: Maggie Kay

Thereís a silent killer out there. It creeps up on its victims, attacks them quietly and unsuspectingly, and initiates a wound that develops over many years before it eventually causes pain. This unstoppable murderer is known as mesothelioma.

Mesothelioma is a malignant tumor that develops on the mesothelial cells of either the lungs, heart or abdominal organs, and plagues those who have been exposed to asbestos for a prolonged period of time. Many who fall victim to this disease are people who have worked in specific trades or fields prior to the 1970s, such as blacksmiths, electricians, millwrights, and oil refinery workers.

Since it can take up to forty years for symptoms to surface, mesothelioma-related deaths are higher than ever in the 21st century. The Centers for Disease Control and Prevention state that 1,493 people died from asbestos in 2000, compared to 77 people in 1968.

Mesothelioma treatment methods differ depending on the stage of the cancer upon detection, as well as....[MORE]

Author:

Standard treatment

options:

1. Symptomatic treatment to include drainage of effusions,

   chest tube

   pleurodesis, or thoracoscopic pleurodesis.

2. Palliative surgical resection

   in selected patients.

3. Palliative radiation therapy.
4. Single-agent chemotherapy. Partial responses have been reported with

   doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin,

   and ifosfamide.

5. Combination chemotherapy (under clinical evaluation). Information

   about ongoing clinical trials is available from the NCI

   Cancer.gov Website.

6. Multimodality clinical trials.
7. Intracavitary

   therapy. Intrapleural or intraperitoneal administration

   of

   chemotherapeutic agents (e.g., cisplatin, mitomycin,

   and cytarabine) has been

   reported to produce transient

   reduction in the size of tumor masses and

   temporary control of effusions in small clinical studies. Additional

   studies are needed to define the role of intra-cavitary therapy.

The safety and efficacy of pemetrexed, an antifolate, and

cisplatin in chemotherapy-n aive patients with malignant mesothelioma

who were not eligible fo....[MORE]

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ACC will this week challenge the right of those dying from asbestos exposure to claim lump-sum compensation.

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Knee deep in asbestos. Now what?
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